Fluctuation-assay p0 mutation-rate estimate

p0 method for independent fluctuation assays with entire cultures assayed, similar final viable counts and negligible initial inoculum under the mutation/growth assumptions. Reports m=-ln(p0) and explicitly uses the m/Nt rate convention. Restricts p0 to the practical0.1–0.7 range. No partial-plating, post-selection mutation or differential-growth correction.

p0 method for independent fluctuation assays with entire cultures assayed, similar final viable counts and negligible initial inoculum under the mutation/growth assumptions. Reports m=-ln(p0) and explicitly uses the m/Nt rate convention. Restricts p0 to the practical0.1–0.7 range. No partial-plating, post-selection mutation or differential-growth correction.

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